Most frequent complaints reported(multiple complaints per patient are possible)
Adverse effect may be due to disease and/or other underlying condition and medication/treatment may not be causative factor
DRUG RATING DETAILS (RANK BASED ON RATINGS OF SIMILAR DRUGS; SEE TABLE AT BOTTOM)
Drug Brand Name
Nymalize
Drug Substance/Generic Name
nimodipine
Number of Patients Complaining
371
Serious Reactions to Substance
360
Non Serious Reactions to Substance
51
Substance Not Effective Complaints
17
At-Ray Ratio (NSR/SR); Safety indicator, higher is safer
0.14
PP Ratio (Patients Complaining/Not Effective), higher is more effective
21.82
Drug Rating = PP Ratio* At-Ray Ratio
2.36
Summary (from Wikipedia)
Nimodipine (marketed by Bayer as Nimotop) is a dihydropyridine calcium channel blocker originally developed for the treatment of high blood pressure. It is not frequently used for this indication, but has shown good results in preventing a major complication of subarachnoid hemorrhage (a form of cerebral hemorrhage) termed vasospasm; this is now the main use of nimodipine.
Indications and Usage (from FDA label)
1 INDICATIONS AND USAGE NYMALIZE is indicated for the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in adult patients with subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms regardless of their post-ictus neurological condition (i.e., Hunt and Hess Grades I-V). NYMALIZE is a dihydropyridine calcium channel blocker indicated for the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in adult patients with subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms regardless of their post-ictus neurological condition (i.e., Hunt and Hess Grades I-V). (1)
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Dihydropyridine derivatives
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